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  1. priligy equivalent chlorothiazide decreases effects of chlorpropamide by pharmacodynamic antagonism

  2. Application Of High-frequency Ultrasound To Assess
    Facial Skin Thickness In Association With Gender, Age, And BMI In Healthy Adults

    Abstract
    This study investigates the application of high-frequency ultrasound to
    assess facial skin thickness in relation to gender, age,
    and body mass index (BMI) in healthy adults. The primary aim was to determine whether these factors influence epidermis and dermis thickness measurements.
    Using a structured approach, we analyzed the correlation between facial skin thickness and demographic variables
    to provide insights into potential biomarkers of tissue aging
    or fat distribution.

    Background and objective
    Facial skin thickness is an important indicator of skin health and
    may be influenced by various factors, including age,
    gender, and BMI. High-frequency ultrasound (HFU) has
    been shown to effectively measure soft tissue depths,
    making it a valuable tool for assessing facial skin thickness.

    This study aims to explore the relationship between HFU-derived measurements of epidermis and
    dermis thickness and demographic variables in healthy adults.

    Methods
    The study employed a cross-sectional design to evaluate facial skin thickness in 100 healthy adults aged 18–65 years.

    Inclusion criteria included no history of skin disease or
    surgery, while exclusion criteria excluded pregnancy and BMI 0.90.
    Ultrasound measurements revealed mean epidermis thickness of 1.2 mm (SD = 0.15) and dermis thickness of
    1.8 mm (SD = 0.20). Correlation analysis showed significant positive relationships between dermis thickness and age
    (r=0.45, p0.90. Ultrasound-derived thickness showed significant positive
    correlations between dermis and age (r=0.45, p0.90.

    Ultrasound measurements of epidermis and dermis thickness
    Mean epidermis thickness = 1.2 mm (SD=0.15), mean dermis thickness = 1.8 mm (SD=0.20).

    Correlation of epidermis and dermis thickness with age and BMI
    Dermis thickness showed significant positive correlation with
    age (r=0.45, p0.90. Ultrasound-derived thickness showed
    significant positive correlations between dermis and age
    (r=0.45, pIsis)

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